Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
… was consistent across various subgroups, the pooled efficacies for PFS, OS, and ORR were
… A phase III RCT compared gefitinib and erlotinib in EGFR mutation-positive NSCLC and …

Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of nonsmall cell lung cancer in patients with common and rare EGFR gene mutations

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… routinely used to treat non-small cell lung cancer (NSCLC) in patients with common activating
mutations of the EGFR gene. The aim of the study was to compare the efficacies of EGFR‑…

A randomized phase II trial of erlotinib vs. S-1 as a third- or fourth-line therapy for patients with wild-type EGFR non-small cell lung cancer (HOT1002)

…, Hokkaido Lung Cancer Clinical Study Group - Cancer chemotherapy …, 2017 - Springer
Erlotinib might have also been recommended as third-line in the 2009 ASCO … efficacy
in patients who received erlotinib as third-line compared with those who received erlotinib as …

Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced nonsmall cell lung cancer: a meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
gefitinib and erlotinib have both been proven effective for treating advanced nonsmall cell
lung cancercompare their efficacy and safety in treating advanced NSCLC in this population. …

Comparing the effects of afatinib with gefitinib or Erlotinib in patients with advanced-stage lung adenocarcinoma harboring non-classical epidermal growth factor …

YC Shen, GC Tseng, CY Tu, WC Chen, WC Liao… - Lung Cancer, 2017 - Elsevier
… IIIb-IV non-small cell lung cancer harboring EGFR classical … the efficacy of gefitinib/erlotinib
and afatinib in patients with … - or third-line treatment, but most patients received EGFR-TKI …

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with nonsmall cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - … and therapeutic …, 2017 - spandidos-publications.com
… reported that, compared with gefitinib, erlotinib possesses an … reported that gefitinib and
erlotinib have similar efficacies (12… toxicity compared with gefitinib for the treatment of advanced

… and safety of gefitinib as third-line treatment in NSCLC patients with activating EGFR mutations treated with first-line gefitinib followed by second-line chemotherapy: a …

Y Song, YL Wu, LJ Cao, JH Chen, ZY Ma… - American Journal of …, 2019 - journals.lww.com
… care for advanced nonsmall cell lung cancer (NSCLC) … 7.7 mo) was observed in
T790M-negative patients compared … of erlotinib for patients with stable disease on prior gefitinib

Erlotinib, cabozantinib, or erlotinib plus cabozantinib as second-line or third-line treatment of patients with EGFR wild-type advanced non-small-cell lung cancer  …

JW Neal, SE Dahlberg, HA Wakelee, SC Aisner… - The lancet …, 2016 - thelancet.com
… We compared the efficacy of cabozantinib alone or in combination with … in the second-line
and third-line setting. We did this trial to directly compare the efficacy of erlotinib with …

Effect of anlotinib as a third-line or further treatment on overall survival of patients with advanced nonsmall cell lung cancer: the ALTER 0303 phase 3 randomized …

B Han, K Li, Q Wang, L Zhang, J Shi, Z Wang… - JAMA …, 2018 - jamanetwork.com
… ’s efficacy in advanced nonsmall cell lung cancer (NSCLC). … in the third-line or beyond
setting that compared a multitarget … TKIs—such as gefitinib, erlotinib hydrochloride, and afatinib …

Anlotinib as a third-line therapy in patients with refractory advanced non-small-cell lung cancer: a multicentre, randomised phase II trial (ALTER0302)

B Han, K Li, Y Zhao, B Li, Y Cheng, J Zhou, Y Lu… - … journal of cancer, 2018 - nature.com
… and efficacy of third-line anlotinib for patients with refractory … erlotinib or gefitinib and have
a PS of 0–3, the efficacy of this … in NSCLC, although direct comparisons of AEs with other …